Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175983 | 0.91 | CSNK2A1 (0.50) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL3659922 | 0.88 | SELL (0.56) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL471443 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL3661233 | 0.84 | KDM4E (0.54) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL909607 | 0.84 | PLAU (0.50) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL11712068 | 0.84 | AKR1C2 (0.46) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL14394630 | 0.82 | APP (0.46) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL6299118 | 0.82 | GAA (0.51) | KDM4EKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3659084 | 0.81 | LMNA (0.55) | KDM4EMEN1KMT2APOLBNSD2 | |
| SCHEMBL17500078 | 0.81 | SMN1; SMN2 (0.63) | KDM4EMEN1KMT2APOLBNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647934-A | Laminate, method for producing laminate, hollow structure, and electronic component | 东丽株式会社 | 2024-09-13 | — | — | CN | disclosed |
| CN-106631730-B | Preparation method and application of fluorescent sensing material based on bis-Schiff base | 江苏大学 | 2020-06-26 | — | — | CN | disclosed |
| US-7872011-B2 | Inhibition of phosphoinositide 3-kinase β | ASTRAZENECA AB (SE) | 2011-01-18 | — | — | US | disclosed |
| US-7872011-B2 | Inhibition of phosphoinositide 3-kinase β | ASTRAZENECA AB (SE) | 2011-01-18 | — | — | US | disclosed |
| US-7872011-B2 | Inhibition of phosphoinositide 3-kinase β | ASTRAZENECA AB (SE) | 2011-01-18 | — | — | US | disclosed |
| US-20100129698-A1 | ELECTRODE CATALYST FOR FUEL CELL | NATIONAL INSTITUTE OF ADVANCED SCIENCE AND TECHNOLOGY (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100129698-A1 | ELECTRODE CATALYST FOR FUEL CELL | NATIONAL INSTITUTE OF ADVANCED SCIENCE AND TECHNOLOGY (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100129698-A1 | ELECTRODE CATALYST FOR FUEL CELL | NATIONAL INSTITUTE OF ADVANCED SCIENCE AND TECHNOLOGY (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2133145-A1 | ELECTRODE CATALYST FOR FUEL CELL | Sumitomo Chemical Company, Limited (JP) | 2009-12-16 | — | — | EP | disclosed |
| US-7598377-B2 | (+-)-7-Methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]pyrimidin-4-one, for example; selective inhibitors of phosphoinositide (PI) 3-kinase beta for use in anti-thrombotic therapy | ASTRAZENECA AB (SE) | 2009-10-06 | — | — | US | disclosed |
| US-7598377-B2 | (+-)-7-Methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]pyrimidin-4-one, for example; selective inhibitors of phosphoinositide (PI) 3-kinase beta for use in anti-thrombotic therapy | ASTRAZENECA AB (SE) | 2009-10-06 | — | — | US | disclosed |
| US-7598377-B2 | (+-)-7-Methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]pyrimidin-4-one, for example; selective inhibitors of phosphoinositide (PI) 3-kinase beta for use in anti-thrombotic therapy | ASTRAZENECA AB (SE) | 2009-10-06 | — | — | US | disclosed |
| US-20080319021-A1 | Inhibition Of Phosphoinositide 3-Kinase Beta | KINACIA PTY. LTD. (AU) | 2008-12-25 | — | — | US | disclosed |
| US-20080319021-A1 | Inhibition Of Phosphoinositide 3-Kinase Beta | KINACIA PTY. LTD. (AU) | 2008-12-25 | — | — | US | disclosed |
| US-20080319021-A1 | Inhibition Of Phosphoinositide 3-Kinase Beta | KINACIA PTY. LTD. (AU) | 2008-12-25 | — | — | US | disclosed |
| US-20060276470-A1 | (+-)-7-Methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]pyrimidin-4-one, for example; selective inhibitors of phosphoinositide (PI) 3-kinase beta for use in anti-thrombotic therapy | ASTRAZENECA AB (SE) | 2006-12-07 | — | — | US | disclosed |
| EP-1537102-A1 | INHIBITION OF PHSPHOINOSTIDE 3-DINASE BETA | Kinacia Pty Ltd. (AU) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004016607-A1 | INHIBITION OF PHOSPHOINOSITIDE 3-KINASE BETA | KINACIA PTY LTD. (AU) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319021-A1 | Inhibition Of Phosphoinositide 3-Kinase Beta | PI4KB, PI4KA, PI4K2B | KDM4E 2002/4885MEN1 2560/4885KMT2A 3584/4885 |
| US-20060276470-A1 | (+-)-7-Methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]pyrimidin-4-one, for example; selective inhibitors of phosphoinositide (PI) 3-kinase beta for use in anti-thrombotic therapy | PI4KA, PI4KB, PI4K2B | KDM4E 1008/4885MEN1 2649/4885KMT2A 2732/4885 |
| US-20090318681-A1 | METAL COMPLEX, AND USE THEREOF | MT-CO1, CYC1, ACAD9 | KDM4E 4791/4885MEN1 762/4885KMT2A 3989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.