Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 4/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13033321 | 0.93 | MEN1 (0.56) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL25698360 | 0.91 | TGM2 (0.57) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL12017845 | 0.90 | MEN1 (0.53) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL14300324 | 0.89 | MEN1 (0.54) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL18760518 | 0.89 | FPR2 (0.56) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL12118351 | 0.89 | MEN1 (0.59) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL10000831 | 0.89 | P2RY6 (0.56) | TGM2MEN1USP2POLBPPARG | |
| Hydrochloric Acid SCHEMBL21112986 | 0.88 | P2RY6 (0.56) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL18760308 | 0.88 | USP2 (0.54) | TGM2MEN1USP2POLBPPARG | |
| SCHEMBL12173012 | 0.88 | TGM2 (0.54) | TGM2MEN1USP2POLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573502-B | Biocompatible modular tetrazine platform | 国家科学研究中心 | 2023-07-18 | — | — | CN | disclosed |
| US-11242359-B2 | Biocompatible modular tetrazine platform | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-02-08 | — | — | US | disclosed |
| US-20200354381-A1 | BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-11-12 | — | — | US | disclosed |
| EP-3609885-A1 | BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM | Centre National De La Recherche Scientifique (FR) | 2020-02-19 | — | — | EP | disclosed |
| CN-110573502-A | biocompatible modular tetrazine platform | 国家科学研究中心 | 2019-12-13 | — | — | CN | disclosed |
| WO-2018172543-A1 | BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-09-27 | — | — | WO | disclosed |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-08-10 | — | — | US | disclosed |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-08-10 | — | — | US | disclosed |
| WO-2015191789-A2 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354381-A1 | BIOCOMPATIBLE MODULAR TETRAZINE PLATFORM | DYRK4, TALDO1, DYRK3 | TGM2 951/4885MEN1 126/4885USP2 1356/4885 |
| US-11242359-B2 | Biocompatible modular tetrazine platform | DYRK4, TALDO1, DYRK3 | TGM2 951/4885MEN1 126/4885USP2 1356/4885 |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | NQO1, NCL, NANS | TGM2 2307/4885MEN1 458/4885USP2 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.