Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707506 | 0.83 | DPP4 (0.38) | DPP4 | |
| SCHEMBL16106366 | 0.71 | HSD11B1 (0.37) | DPP4 | |
| SCHEMBL27510109 | 0.70 | EPHX1 (0.39) | DPP4 | |
| SCHEMBL574102 | 0.70 | BTK (0.36) | DPP4 | |
| SCHEMBL24577501 | 0.70 | DPP4 (0.56) | DPP4 | |
| SCHEMBL27623896 | 0.70 | DPP4 (0.36) | DPP4 | |
| SCHEMBL16200883 | 0.70 | DPP4 (0.39) | DPP4 | |
| SCHEMBL16265413 | 0.69 | EPHX1 (0.35) | DPP4 | |
| SCHEMBL7746771 | 0.69 | DPP4 (0.36) | DPP4 | |
| SCHEMBL871258 | 0.69 | GAA (0.37) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605963-B1 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | PROVID PHARMACEUTICALS INC (US) | 2011-11-16 | — | — | EP | disclosed |
| EP-1605963-A4 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | PROVID PHARMACEUTICALS INC (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1605963-A2 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | Provid Pharmaceuticals, Inc. (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004073625-A2 | INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF | PROVID PHARMACEUTICALS, INC. (US) | 2004-09-02 | — | — | WO | disclosed |