Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 9/20 | 0.66 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.66 |
| ▸ | PARP1 | P09874 | 5/20 | 0.66 |
| ▸ | GUSB | P08236 | 6/20 | 0.65 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617083 | 0.89 | TNKS (0.77) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL878157 | 0.83 | GUSB (0.69) | TNKSTNKS2PARP1GUSBCYP1A1 | |
| SCHEMBL29592833 | 0.80 | TNKS (1.00) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL258433 | 0.80 | TNKS (1.00) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL16007672 | 0.79 | GUSB (1.00) | TNKSTNKS2PARP1GUSBHPGD | |
| Hydrochloric Acid SCHEMBL31529601 | 0.78 | TNKS (0.96) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL878156 | 0.78 | GUSB (0.66) | TNKSTNKS2GUSBCYP1A1CYP1B1 | |
| SCHEMBL11311043 | 0.78 | TNKS (0.70) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL14259681 | 0.78 | TNKS (0.66) | TNKSTNKS2PARP1GUSBKDM4C | |
| SCHEMBL259245 | 0.78 | TNKS (0.71) | TNKSTNKS2PARP1GUSBKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191640-A2 | BICYCLIC XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 2015-12-17 | — | — | WO | disclosed |