Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 13/20 | 0.71 |
| ▸ | TNKS2 | Q9H2K2 | 13/20 | 0.71 |
| ▸ | PARP1 | P09874 | 9/20 | 0.71 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.70 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135157 | 0.89 | TNKS (0.73) | TNKSTNKS2PARP1PARP2KDM4C | |
| SCHEMBL8270073 | 0.87 | TNKS (0.70) | TNKSTNKS2PARP1PARP2TUBB4A | |
| SCHEMBL2617083 | 0.85 | TNKS (0.77) | TNKSTNKS2PARP1PARP2KDM4C | |
| SCHEMBL277870 | 0.84 | TNKS (0.56) | TNKSTNKS2PARP1PARP2TUBB4A | |
| SCHEMBL16965507 | 0.83 | TNKS (0.69) | TNKSTNKS2PARP1PARP2TUBB4A | |
| SCHEMBL16965224 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL27694097 | 0.83 | TNKS (0.58) | TNKSTNKS2PARP1HPGDGUSB | |
| SCHEMBL8618982 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1PARP2ALDH1A1 | |
| SCHEMBL259610 | 0.82 | GUSB (0.74) | TNKSTNKS2PARP1PARP2MAPT | |
| SCHEMBL20665778 | 0.81 | ALDH1A1 (0.70) | TNKSTNKS2PARP1PARP2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118125985-A | Method for preparing quinazolinone by activating alkylbenzene benzyl site C (sp 3) -H bond by photo-generated chlorine free radical | 桂林理工大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-115650924-A | Green synthesis method of quinazolinone | 上海橡实化学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113185468-B | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-113185468-A | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-106518789-B | A method of synthesis Quinazol derivative | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106518789-A | Method for synthesis of quinazolinone derivative | 南京理工大学 | 2017-03-22 | — | — | CN | disclosed |
| US-8067586-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-8067586-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| EP-1277738-B1 | CONDENSED HETEROARYL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20100137585-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20100137585-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20070037805-A1 | Fused heteroaryl derivatives | HAYAKAWA MASAHIKO | 2007-02-15 | — | — | US | disclosed |
| US-20070037805-A1 | Fused heteroaryl derivatives | HAYAKAWA MASAHIKO | 2007-02-15 | — | — | US | disclosed |
| US-7173029-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-7173029-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | PIK3CD, PIK3R3, PIK3C2A | TNKS 578/4885TNKS2 487/4885PARP1 1165/4885 |
| US-20070037805-A1 | Fused heteroaryl derivatives | PIK3CD, PIK3R3, PIK3C2A | TNKS 578/4885TNKS2 487/4885PARP1 1165/4885 |
| US-20100137585-A1 | FUSED HETEROARYL DERIVATIVES | PIK3CD, PIK3R3, PIK3C2A | TNKS 578/4885TNKS2 487/4885PARP1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.