SCHEMBL17348784

SCHEMBL17348784

Brc1cccc2c1c1cccnc1n2-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDE4A P27815 7/20 0.42
PDE4B Q07343 6/20 0.42
PDE4C Q08493 6/20 0.42
PDE4D Q08499 6/20 0.42
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDE1A P54750 1/20 0.39
PDE1B Q01064 1/20 0.39
LDHA P00338 1/20 0.39
REN P00797 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22373830 0.82 ALDH1A1 (0.48) FEN1ALDH1A1TSHRCYP2C19PDE4A
SCHEMBL20172238 0.82 FEN1 (0.46) FEN1ALDH1A1TSHRCYP2C19PDE4A
SCHEMBL17349052 0.81 KDM4E (0.47) FEN1ALDH1A1TSHRCYP2C19PDE4A
SCHEMBL21398092 0.81 KDM4E (0.36) ALDH1A1TSHRKDM4EATML3MBTL1
SCHEMBL29446458 0.79 L3MBTL1 (0.61) ALDH1A1TSHRCYP2C19KDM4EATM
SCHEMBL5021401 0.79 KDM4E (0.61) FEN1ALDH1A1TSHRCYP2C19PDE4A
SCHEMBL3049158 0.79 L3MBTL1 (0.61) ALDH1A1TSHRCYP2C19KDM4EATM
SCHEMBL31384383 0.79 L3MBTL1 (0.61) ALDH1A1TSHRCYP2C19KDM4EATM
SCHEMBL25708769 0.79 FEN1 (0.43) FEN1ALDH1A1TSHRCYP2C19PDE4A
SCHEMBL17348785 0.79 L3MBTL1 (0.47) FEN1ALDH1A1TSHRCYP2C19PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074926-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof DUK SAN NEOLUX CO LTD (KR) 2021-03-11 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
WO-2015190867-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210074926-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof OR10J3, OR51E2, ETV6 FEN1 2075/4885ALDH1A1 956/4885TSHR 4810/4885
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF OR10J3, OR51E2, ETV6 FEN1 2075/4885ALDH1A1 956/4885TSHR 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.