Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243735 | 1.00 | POLB (0.45) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL17350908 | 0.87 | ALDH1A1 (0.53) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL10243899 | 0.87 | ALDH1A1 (0.53) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL10243662 | 0.87 | HSD11B1 (0.47) | PARP10SLC18A3SIGMAR1HSD11B1HRH3 | |
| SCHEMBL17350615 | 0.87 | HSD11B1 (0.47) | PARP10SLC18A3SIGMAR1HSD11B1HRH3 | |
| SCHEMBL17350984 | 0.86 | POLB (0.57) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL10243883 | 0.86 | POLB (0.57) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL10243880 | 0.83 | POLB (0.51) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL17350934 | 0.83 | POLB (0.51) | POLBPARP10SLC18A3SIGMAR1HSD11B1 | |
| SCHEMBL10243827 | 0.83 | POLB (0.51) | POLBPARP10SLC18A3SIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318403-B1 | Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INT (DE) | 2015-12-23 | — | — | EP | disclosed |