Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HLCS | P50747 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510062 | 1.00 | ALOX5 (0.36) | ALOX5GHSRFAAHNAAACYP1A2 | |
| SCHEMBL3332909 | 0.93 | ALDH1A1 (0.39) | ALOX5GHSRFAAHNAAACYP1A2 | |
| SCHEMBL21815505 | 0.79 | SLC6A2 (0.42) | ALDH1A1 | |
| SCHEMBL28502803 | 0.73 | CYP1A2 (0.37) | ALOX5FAAHCYP1A2GNAO1ALDH1A1 | |
| SCHEMBL6861565 | 0.73 | CYP1A2 (0.42) | ALOX5CYP1A2ALDH1A1L3MBTL1GBA1 | |
| SCHEMBL3652550 | 0.73 | CYP1A2 (0.42) | ALOX5CYP1A2ALDH1A1L3MBTL1GBA1 | |
| SCHEMBL3792450 | 0.71 | CYP1A2 (0.41) | ALOX5FAAHCYP1A2GNAO1GBA1 | |
| SCHEMBL4486955 | 0.71 | CYP1A2 (0.41) | ALOX5FAAHCYP1A2GNAO1GBA1 | |
| SCHEMBL31026188 | 0.71 | CYP1A2 (0.41) | ALOX5FAAHCYP1A2GNAO1GBA1 | |
| SCHEMBL8333332 | 0.71 | CYP1A2 (0.41) | ALOX5FAAHCYP1A2GNAO1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024939-A1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | RECURIUM IP HOLDINGS, LLC | 2022-01-27 | — | — | US | disclosed |
| US-9216999-B2 | Substituted pyrrolo[2,3-h][1,6]naphthyridines and compositions thereof as JAK inhibitors | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024939-A1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | MKI67, BRCA1, CCNI | ALOX5 2737/4885GHSR 2767/4885FAAH 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.