Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507275 | 0.91 | TSHR (0.55) | TSHRALDH1A1TDP1TP53PPARD | |
| SCHEMBL31121629 | 0.89 | CYP3A4 (0.53) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL4266926 | 0.88 | TSHR (0.46) | TSHRALDH1A1LMNATP53CES2 | |
| SCHEMBL6670269 | 0.87 | TSHR (0.50) | TSHRLMNATDP1TP53PPARD | |
| SCHEMBL1117108 | 0.86 | ALDH1A1 (0.55) | TSHRALDH1A1LMNACES2CES1 | |
| SCHEMBL28755999 | 0.86 | DGKA (0.47) | TSHRLMNA | |
| SCHEMBL28156891 | 0.85 | ALDH1A1 (0.44) | TSHRALDH1A1LMNAPPARDCES2 | |
| SCHEMBL4275995 | 0.84 | DGKA (0.50) | LMNACES2CES1 | |
| SCHEMBL4598746 | 0.84 | ALDH1A1 (0.52) | TSHRALDH1A1LMNACES2CES1 | |
| SCHEMBL7507280 | 0.83 | TSHR (0.46) | TSHRALDH1A1LMNATDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139862-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118119629-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-112566637-A | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112533674-A | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3020700-B1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-10077401-B2 | Polymerizable compound, polymerizable composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-09-18 | — | — | US | disclosed |
| EP-0881221-B1 | DIOXANE DERIVATIVES, LIQUID-CRYSTAL COMPOSITIONS CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY DEVICES MADE BY USING THE SAME | JNC CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-20160152895-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| EP-3020700-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-2336217-B1 | POLYESTER POLYMERIZATION CATALYST AND METHOD FOR PRODUCING POLYESTER USING SAME | TORAY INDUSTRIES (JP) | 2015-01-14 | — | — | EP | disclosed |
| EP-0272583-B1 | 5-SUBSTITUTED AMINO-4-HYDROXY-PENTENOIC ACID DERIVATIVES AND THEIR USE | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0527185-A1 | AMETHOPTERIN(METHOTREXATE) PRO-DRUGS, INTERMEDIATE PRODUCTS, A PREPARATION METHOD, AND COMPOSITIONS CONTAINING THEM. | UNIV BRETAGNE OCCIDENTALE (FR) | 1993-02-17 | — | — | EP | disclosed |
| US-5122523-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| WO-1991016330-A1 | AMETHOPTERIN(METHOTREXATE) PRO-DRUGS, INTERMEDIATE PRODUCTS, A PREPARATION METHOD, AND COMPOSITIONS CONTAINING THEM | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 1991-10-31 | — | — | WO | disclosed |
| US-4927565-A | HYPOTENSIVE AGENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |
| EP-0272583-A2 | 5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-06-29 | — | — | EP | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152895-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CCDC47, NCAPD2, CCDC22 | TSHR 4548/4885ALDH1A1 4340/4885LMNA 1891/4885 |
| US-10077401-B2 | Polymerizable compound, polymerizable composition and liquid crystal display device | CCDC47, NCAPD2, CCDC22 | TSHR 4548/4885ALDH1A1 4340/4885LMNA 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.