SCHEMBL17352134

SCHEMBL17352134

C=C(C)C(=O)Oc1ccc(F)c(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
CDK8 P49336 2/20 0.39
AR P10275 2/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
KIF11 P52732 1/20 0.37
PLA2G7 Q13093 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
TAS1R2 Q8TE23 2/20 0.36
ACACB O00763 1/20 0.35
KMO O15229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17355655 0.88 CDK8 (0.41) CDK8ARHTR2ASLC6A4KCNH2
SCHEMBL15836530 0.88 ELANE (0.46) ELANEKMT2AATMARPOLB
SCHEMBL17352128 0.87 CDK8 (0.44) CDK8ARHTR2ASLC6A4KCNH2
SCHEMBL17356316 0.87 POLB (0.38) CDK8ARHTR2ASLC6A4KCNH2
SCHEMBL26793677 0.85 ELANE (0.44) ELANEKMT2AATMARPOLB
SCHEMBL1893249 0.84 LMNA (0.44) KMT2ACDK8ARHTR2ASLC6A4
SCHEMBL17352140 0.83 CDK8 (0.43) CDK8ARHTR2ASLC6A4KCNH2
SCHEMBL17356444 0.82 POLB (0.39) CDK8ARHTR2ASLC6A4KCNH2
SCHEMBL12636054 0.82 ELANE (0.50) ELANEKMT2AATMPOLBMAPT
SCHEMBL17355788 0.82 POLB (0.40) CDK8ARHTR2ASLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US claimed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 ELANE 570/4885KMT2A 2355/4885ATM 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.