Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | NRP1 | O14786 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366371 | 0.92 | OPRM1 (0.46) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL17352470 | 0.92 | OPRM1 (0.46) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL17352458 | 0.91 | OPRM1 (0.43) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL29355564 | 0.88 | GRB2 (0.47) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL17352464 | 0.86 | OPRM1 (0.40) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL31065472 | 0.85 | OPRM1 (0.45) | OPRM1GRB2F2 | |
| SCHEMBL29374739 | 0.85 | OPRM1 (0.45) | OPRM1GRB2F2 | |
| SCHEMBL29776753 | 0.85 | OPRM1 (0.48) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL29886469 | 0.85 | OPRM1 (0.46) | OPRM1KDM4EMAPTALOX15PTGS2 | |
| SCHEMBL29363345 | 0.84 | OPRM1 (0.46) | OPRM1GRB2XIAPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170095445-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170095445-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170095445-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC (US) | 2017-04-06 | — | — | US | disclosed |
| US-20150368197-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC. | 2015-12-24 | — | — | US | disclosed |
| US-20150368197-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC. | 2015-12-24 | — | — | US | disclosed |
| US-20150368197-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC. | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368197-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | ELANE, CYSLTR1, CYSLTR2 | OPRM1 2940/4885KDM4E 4780/4885MAPT 4002/4885 |
| US-20170095445-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | MPO, ELANE, CYSLTR2 | OPRM1 2977/4885KDM4E 4764/4885MAPT 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.