SCHEMBL1735325

SCHEMBL1735325

CCn1c(C)c(C)c2ccnc(CNc3ccc(F)cc3)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MAPT P10636 4/20 0.37
RAB9A P51151 4/20 0.37
ALDH1A1 P00352 3/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
ALOX12 P18054 1/20 0.37
MPI P34949 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPC1 O15118 2/20 0.36
AURKA O14965 1/20 0.35
ABL1 P00519 1/20 0.35
NTRK1 P04629 1/20 0.35
LCK P06239 1/20 0.35
CSF1R P07333 1/20 0.35
RET P07949 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1737751 0.99 GAA (0.38) GAAMAPTRAB9AALDH1A1KMT2A
SCHEMBL1737369 0.91 RAB9A (0.38) GAAMAPTRAB9AALDH1A1KMT2A
Hydrochloric Acid SCHEMBL1736130 0.90 RAB9A (0.37) GAAMAPTRAB9AALDH1A1KMT2A
SCHEMBL1735560 0.86 KMT2A (0.37) MAPTRAB9AALDH1A1KMT2AL3MBTL1
SCHEMBL1737079 0.86 KMT2A (0.36) MAPTRAB9AALDH1A1KMT2AL3MBTL1
SCHEMBL1738007 0.86 MAPT (0.36) MAPTRAB9AALDH1A1KMT2AL3MBTL1
SCHEMBL1738308 0.85 AURKA (0.44) GAAMAPTRAB9AALDH1A1KMT2A
SCHEMBL1738229 0.85 MAPT (0.46) GAAMAPTRAB9AALDH1A1KMT2A
SCHEMBL1738965 0.85 MAPT (0.37) GAAMAPTRAB9AALDH1A1KMT2A
SCHEMBL1738022 0.85 CYP1A2 (0.36) GAAMAPTRAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP disclosed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US disclosed