Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354606 | 0.91 | UCHL1 (0.32) | TP53MAPTTHRBLMNA | |
| SCHEMBL12094442 | 0.89 | TP53 (0.36) | TP53MAPTTHRBLMNA | |
| SCHEMBL12092304 | 0.86 | TP53 (0.40) | TP53MAPTTHRBLMNA | |
| SCHEMBL4153027 | 0.75 | MAPT (0.50) | TP53MAPTTHRBLMNA | |
| SCHEMBL17354603 | 0.72 | MAPT (0.52) | TP53MAPTTHRBLMNA | |
| SCHEMBL2996787 | 0.69 | MAPT (0.52) | TP53MAPTTHRBLMNA | |
| SCHEMBL2981865 | 0.69 | MAPT (0.42) | TP53MAPTTHRBLMNA | |
| SCHEMBL17685231 | 0.68 | MAPT (0.41) | TP53MAPTTHRBLMNA | |
| SCHEMBL2987929 | 0.68 | PIM1 (0.33) | TP53MAPTTHRB | |
| SCHEMBL2992714 | 0.67 | MAPT (0.47) | TP53MAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216966-B2 | Compounds for Alzheimer's disease | Manfredi, John (US) | 2015-12-22 | — | — | US | disclosed |