Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 9/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737607 | 0.98 | TDO2 (0.58) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1736399 | 0.87 | BCHE (0.51) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1737859 | 0.84 | BCHE (0.58) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1735797 | 0.84 | TDO2 (0.58) | TDO2HTR2BHTR5ABCHENQO2 | |
| Hydrochloric Acid SCHEMBL1737608 | 0.83 | TDO2 (0.57) | TDO2HTR2BHTR5ABCHENQO2 | |
| Hydrochloric Acid SCHEMBL1738504 | 0.83 | BCHE (0.57) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1736630 | 0.82 | HTR2B (0.65) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1735593 | 0.81 | BCHE (0.41) | TDO2HTR2BHTR5ABCHENQO2 | |
| SCHEMBL1736683 | 0.81 | BCHE (0.53) | TDO2HTR2BHTR5ABCHEIDO1 | |
| SCHEMBL1737727 | 0.81 | HTR2B (0.64) | TDO2HTR2BHTR5ABCHENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |
| US-8188114-B2 | Pyrrolo[2,3-C]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2012-05-29 | — | — | US | disclosed |
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | disclosed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20100069430-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2010-03-18 | — | — | US | disclosed |
| US-7662832-B2 | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-02-16 | — | — | US | disclosed |
| US-20070219230-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069430-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, ATP6V1H | TDO2 433/4885HTR2B 1231/4885HTR5A 784/4885 |
| US-20070219230-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, ATP6V1H | TDO2 433/4885HTR2B 1231/4885HTR5A 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.