SCHEMBL17355758

SCHEMBL17355758

COC(=O)Oc1cc(C)cc(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 5/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 2/20 0.39
RAPGEF4 Q8WZA2 2/20 0.35
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.34
HDAC3 O15379 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29320483 0.89 CYP4F2 (0.43) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL28452476 0.88 CYP4F2 (0.46) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL8426699 0.86 MEN1 (0.49) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17355792 0.84 CYP4F2 (0.40) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL16950367 0.81 CYP4F2 (0.61) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL29177324 0.79 MEN1 (0.44) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL17356468 0.77 SCN9A (0.46) CYP4F2CYP4A11MAPTHDAC3HDAC1
SCHEMBL9237989 0.77 KMT2A (0.42) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL17355768 0.77 HDAC1 (0.46) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL3829975 0.75 MEN1 (0.48) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 CYP4F2 1855/4885CYP4A11 3065/4885MEN1 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.