SCHEMBL16950367

SCHEMBL16950367

CC(=O)Oc1cc(C)cc(F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.61
CYP4A11 Q02928 1/20 0.61
LMNA P02545 3/20 0.53
ELANE P08246 2/20 0.45
MAPT P10636 5/20 0.41
KDM4E B2RXH2 4/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 1/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ACHE P22303 2/20 0.40
BACE1 P56817 1/20 0.40
CYP19A1 P11511 1/20 0.38
ALDH1A1 P00352 2/20 0.37
GLA P06280 2/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995396 0.87 CYP4F2 (0.69) CYP4F2CYP4A11LMNAELANEMAPT
SCHEMBL1701666 0.85 LMNA (0.63) CYP4F2CYP4A11LMNAELANEMAPT
SCHEMBL593772 0.85 LMNA (0.63) CYP4F2CYP4A11LMNAELANEMAPT
SCHEMBL29320483 0.84 CYP4F2 (0.43) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL28793573 0.83 LMNA (0.61) CYP4F2CYP4A11LMNAELANEMAPT
SCHEMBL29177324 0.82 MEN1 (0.44) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL17355758 0.81 CYP4F2 (0.41) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL24445873 0.80 CYP4F2 (0.61) CYP4F2CYP4A11LMNAELANEMAPT
SCHEMBL23183033 0.80 CYP4F2 (0.40) CYP4F2CYP4A11LMNAMAPTMEN1
SCHEMBL17355792 0.79 CYP4F2 (0.40) CYP4F2CYP4A11LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 CYP4F2 1855/4885CYP4A11 3065/4885LMNA 1291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.