Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | PRKCZ | Q05513 | 10/20 | 0.67 |
| ▸ | PRKCI | P41743 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271891 | 0.88 | PRKCZ (0.68) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL17359213 | 0.85 | PRKCZ (0.70) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL17356378 | 0.85 | MAPT (0.72) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL14123479 | 0.82 | PRKCZ (0.66) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL690278 | 0.82 | PRKCZ (0.84) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL10297769 | 0.82 | PRKCZ (0.70) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL13838035 | 0.81 | PRKCZ (0.83) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL12632700 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL31060884 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL13926187 | 0.79 | ALDH1A1 (0.70) | MAPTALDH1A1HSD17B10MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301965-B2 | Method of treating ovarian cancer using a PKC inhibitor | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150366883-A1 | METHOD OF TREATING OVARIAN CANCER USING A PKC INHIBITOR | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366883-A1 | METHOD OF TREATING OVARIAN CANCER USING A PKC INHIBITOR | PRKD1, PRKCI, ACP3 | MAPT 4352/4885ALDH1A1 3055/4885HSD17B10 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.