SCHEMBL17356558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17359237	0.98	AKR1C3 (0.34)	AKR1C3AKR1C2RAPGEF4PTGS2PTGS1
	SCHEMBL17359298	0.90	PTGS2 (0.38)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL13104726	0.89	AKR1C3 (0.34)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL16852357	0.85	AKR1C3 (0.47)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL18134234	0.83	AKR1C3 (0.46)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL17356575	0.83	AKR1C3 (0.34)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL18069656	0.82	AKR1C3 (0.42)	AKR1C3AKR1C2PTGS2PTGS1AKR1B10
	SCHEMBL18069651	0.82	AKR1C3 (0.53)	AKR1C3AKR1C2PTGS2AKR1B10AKR1C4
	SCHEMBL803253	0.81	PTGS2 (0.38)	AKR1C3AKR1C2PTGS2PTGS1ESR2
	SCHEMBL17359262	0.81	RPS6KA3 (0.46)	PTGS2PTGS1PDE3BPDE3AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.