Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743481 | 0.80 | CHRM2 (0.71) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL2329949 | 0.78 | ALDH1A1 (0.37) | KMT2AALDH1A1TSHR | |
| SCHEMBL18523282 | 0.76 | CHRM2 (0.61) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL3207101 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL3207097 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12714339 | 0.74 | CHRM2 (0.68) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL2326669 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10447494 | 0.72 | CHRM2 (0.66) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL11180560 | 0.71 | NR2C2 (0.38) | ALDH1A1TSHR | |
| SCHEMBL5171242 | 0.71 | CHRM2 (0.69) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029587-B1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA AS (CZ) | 2015-09-02 | — | — | EP | disclosed |
| EP-2094693-B1 | A METHOD FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA KS (CZ) | 2011-11-16 | — | — | EP | disclosed |
| US-20110264760-A1 | METHOD AND APPARATUS PROVIDING FOR OUTPUT OF A CONTENT PACKAGE BY AN APPLICATION BASED AT LEAST IN PART ON A CONTENT TYPE SELECTION AND ONE OR MORE CONTEXTUAL CHARACTERISTICS | NOKIA CORPORATION | 2011-10-27 | — | — | US | disclosed |
| US-8034942-B2 | Process for the preparation of solifenacin | Zentiva k s. (CZ) | 2011-10-11 | — | — | US | disclosed |
| US-20100145055-A1 | METHOD FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA K.S. (CZ) | 2010-06-10 | — | — | US | disclosed |
| EP-2094693-A2 | A METHOD FOR THE PREPARATION OF SOLIFENACIN | Zentiva, k.s. (CZ) | 2009-09-02 | — | — | EP | disclosed |
| US-20090203914-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA K.S. (CZ) | 2009-08-13 | — | — | US | disclosed |
| EP-2029587-A2 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | Zentiva, A.S. (CZ) | 2009-03-04 | — | — | EP | disclosed |
| WO-2008077357-A2 | A METHOD FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA, A.S. (CZ) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007147374-A2 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA A.S. (CZ) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145055-A1 | METHOD FOR THE PREPARATION OF SOLIFENACIN | CHRNA3, CHRM3, CHRNA1 | CHRM2 20/4885CHRM1 24/4885CYP2D6 1813/4885 |
| US-20090203914-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | OPRL1, CHRNG, CHRM1 | CHRM2 19/4885CHRM1 3/4885CYP2D6 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.