SCHEMBL17358237

SCHEMBL17358237

Cc1cc(OCc2ccccc2)c2c(=O)c(O[Si](C)(C)C(C)(C)C)c(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)oc2c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.47
ELANE P08246 4/20 0.45
PLG P00747 3/20 0.45
ACE2 Q9BYF1 2/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
KMT2A Q03164 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17358238 0.92 ACE2 (0.52) PPARGACE2KDM4EHSD17B10MEN1
SCHEMBL23965813 0.91 PPARG (0.54) PPARGELANEPLGACE2ADORA3
SCHEMBL15450248 0.89 PPARG (0.59) PPARGELANEPLGACE2ADORA3
SCHEMBL23965831 0.86 ACE2 (0.59) PPARGPLGACE2ADORA3MAPT
SCHEMBL17523242 0.79 PPARG (0.64) PPARGELANEPLGKDM4EALDH1A1
Benzquercin SCHEMBL1057326 0.78 PPARG (0.66) PPARGELANEPLGACE2ADORA3
SCHEMBL20630735 0.76 ADORA3 (0.69) PPARGELANEPLGACE2ADORA3
SCHEMBL31236659 0.76 ADORA3 (0.69) PPARGELANEPLGACE2ADORA3
SCHEMBL12856640 0.75 ACE2 (0.53) PPARGELANEPLGACE2KDM4E
SCHEMBL17358242 0.75 CYP1A1 (0.53) PPARGELANEACE2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556140-B2 Approach for synthesis of catechins SPHAERA PHARMA PVT. LTD. (IN) 2017-01-31 US disclosed
US-20150368223-A1 NOVEL APPROACH FOR SYNTHESIS OF CATECHINS EPIRIUM BIO INC. 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368223-A1 NOVEL APPROACH FOR SYNTHESIS OF CATECHINS NQO1, COMT, NNMT PPARG 1126/4885ELANE 266/4885PLG 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.