SCHEMBL17358735

SCHEMBL17358735

C=CCN1C(=O)C(Cc2ccccc2)C(=O)N(CC=C)C1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.66
ALDH1A1 P00352 5/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
APEX1 P27695 1/20 0.44
F2 P00734 1/20 0.43
PLG P00747 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
CTRC Q99895 1/20 0.43
MAPT P10636 3/20 0.43
POLB P06746 3/20 0.43
USP2 O75604 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15131570 0.80 EP300 (1.00) EP300ALDH1A1F2PLGELANE
SCHEMBL8728068 0.78 GAA (0.55) ALDH1A1POLBMEN1KMT2AKDM4E
SCHEMBL1597896 0.75 GAA (0.70) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL3111869 0.74 GAA (0.50) EP300ALDH1A1LMNATHRBAPEX1
SCHEMBL3111866 0.74 GAA (0.50) EP300ALDH1A1LMNATHRBAPEX1
SCHEMBL14513870 0.73 MAPT (0.44) EP300ALDH1A1MAPTPOLBMEN1
SCHEMBL17300518 0.72 EP300 (0.82) EP300ALDH1A1F2PLGELANE
SCHEMBL11274497 0.72 HDAC6 (0.56) EP300F2PLGELANECTSG
SCHEMBL4435666 0.70 KMT2A (0.72) EP300ALDH1A1THRBMAPTPOLB
SCHEMBL19228015 0.70 MAPT (0.42) ALDH1A1MAPTPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed