Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | KDM4A | O75164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17717914 | 0.90 | ALDH1A1 (0.72) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL17358747 | 0.90 | KMT2A (0.65) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL15978122 | 0.87 | MAPT (0.60) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL17358734 | 0.87 | KDM4C (0.62) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL17717935 | 0.86 | KMT2A (0.61) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL17717913 | 0.83 | KMT2A (0.62) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL15978256 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL31424239 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL28013429 | 0.81 | KMT2A (0.52) | KMT2AMEN1KDM4CMAPTALDH1A1 | |
| SCHEMBL17294178 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1KDM4CMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912057-A | A method of barbituric acid derivatives are replaced by amine catalytic air oxidation green syt 5- hydroxyl -5- alkyl two | 河南大学 | 2018-11-30 | — | — | CN | claimed |
| EP-2081576-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | Taro Pharmaceuticals North America, Inc. (KY) | 2009-07-29 | — | — | EP | claimed |
| WO-2008066704-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | TARO PHARMACEUTICALS NORTH AMERICA, INC. (KY) | 2008-06-05 | — | — | WO | claimed |
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-06-05 | — | — | US | claimed |
| CN-1291720-C | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2006-12-27 | — | — | CN | claimed |
| EP-1485101-A4 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMA IND (IL) | 2006-04-12 | — | — | EP | claimed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | claimed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | claimed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | claimed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | claimed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | claimed |
| US-20240343848-A1 | FREE-RADICALLY POLYMERIZABLE COMPOSITION, METHOD OF POLYMERIZING THE SAME, AND POLYMERIZED COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2024-10-17 | — | — | US | disclosed |
| EP-4423191-A1 | PHOTOPOLYMERIZABLE COMPOSITION, METHODS OF BONDING AND SEALING, AND AT LEAST PARTIALLY POLYMERIZED COMPOSITION | 3M Innovative Properties Company (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-117836333-A | Free radically polymerizable composition, method of polymerization, and polymerized composition | 3M创新有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-11897977-B2 | Photolabile barbiturate compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-02-13 | — | — | US | disclosed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | disclosed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | disclosed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | disclosed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | disclosed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | MTNR1B, GABRB3, GABBR1 | KMT2A 1862/4885MEN1 1891/4885KDM4C 1141/4885 |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | GABRA5, GABRA1, GABRA3 | KMT2A 1865/4885MEN1 3949/4885KDM4C 3945/4885 |
| US-11897977-B2 | Photolabile barbiturate compounds | PPOX, CBR1, CBR3 | KMT2A 3332/4885MEN1 4096/4885KDM4C 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.