SCHEMBL17358744

SCHEMBL17358744

O=C1NC(=O)C(Cc2ccc(-c3ccccc3)cc2)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
GSK3B P49841 2/20 0.46
MAPT P10636 3/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MMP2 P08253 2/20 0.42
MMP9 P14780 2/20 0.42
MMP3 P08254 1/20 0.42
FFAR1 O14842 1/20 0.42
DAO P14920 1/20 0.41
ABCC4 O15439 1/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
PTGS1 P23219 1/20 0.40
HTT P42858 1/20 0.40
MMP8 P22894 1/20 0.40
CES2 O00748 1/20 0.40
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320007 0.89 HSD17B10 (0.53) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL12258527 0.83 HDAC8 (0.47) GSK3BALDH1A1GAADAOABCC4
SCHEMBL2673069 0.78 HSD17B10 (0.46) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL30020109 0.78 GAA (0.54) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL7734085 0.78 HSD17B10 (0.46) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL15978113 0.78 HSD17B10 (0.46) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL13045671 0.77 ALDH1A1 (0.44) HSD17B10GSK3BMAPTALDH1A1TSHR
SCHEMBL30019844 0.76 CXCR4 (0.46) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL13045107 0.76 CXCR4 (0.46) HSD17B10GSK3BMAPTALDH1A1GAA
SCHEMBL17070929 0.76 GSK3B (0.58) GSK3BMAPTALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed