Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402315 | 0.81 | GAA (0.42) | MAPTTP53LMNAFFAR1PPARA | |
| SCHEMBL2673069 | 0.81 | HSD17B10 (0.46) | HSD17B10MAPTGSK3BGAAKDM4E | |
| SCHEMBL30020109 | 0.81 | GAA (0.54) | HSD17B10MAPTGSK3BCES2GAA | |
| SCHEMBL15978113 | 0.81 | HSD17B10 (0.46) | HSD17B10MAPTGSK3BGAAKDM4E | |
| SCHEMBL320007 | 0.80 | HSD17B10 (0.53) | HSD17B10MAPTGSK3BGAAKDM4E | |
| SCHEMBL2672578 | 0.79 | HSD17B10 (0.45) | HSD17B10MAPTTP53LMNAFFAR1 | |
| SCHEMBL17358744 | 0.78 | HSD17B10 (0.47) | HSD17B10MAPTLMNAFFAR1GSK3B | |
| SCHEMBL13045671 | 0.77 | ALDH1A1 (0.44) | HSD17B10MAPTTP53GSK3BCES2 | |
| SCHEMBL2673406 | 0.77 | NPSR1 (0.58) | HSD17B10MAPTALDH1A1 | |
| SCHEMBL15419596 | 0.77 | HSD17B10 (0.42) | HSD17B10MAPTTP53GSK3BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413936-B1 | RHEUMATIC DISORDERS; ANTIISCHEMIC AGENTS | GLYCOREX AB (SE) | 2002-07-02 | — | — | US | disclosed |