Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674273 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| SCHEMBL9328559 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| SCHEMBL12640554 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| SCHEMBL12325097 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| SCHEMBL936358 | 0.92 | ALDH1A1 (0.68) | ALDH1A1TDP1OPRM1CYP3A4TSHR | |
| SCHEMBL20962107 | 0.92 | ALDH1A1 (0.68) | ALDH1A1TDP1OPRM1CYP3A4TSHR | |
| SCHEMBL27531285 | 0.91 | ALDH1A1 (0.56) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL10716228 | 0.90 | ALDH1A1 (0.65) | ALDH1A1TDP1OPRM1CYP3A4TSHR | |
| SCHEMBL1261716 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TDP1OPRM1CYP3A4LMNA | |
| SCHEMBL23560995 | 0.88 | DNM1 (0.62) | ALDH1A1TDP1OPRM1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408950-B2 | Immobilised biological entities | W.L. GORE & ASSOCIATES, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150367040-A1 | IMMOBILISED BIOLOGICAL ENTITIES | GORE ENTERPRISE HOLDINGS, INC. | 2015-12-24 | — | — | US | disclosed |