Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737041 | 0.99 | PIK3CB (0.42) | PIK3CBPIK3CDPIK3CANAPEPLDATR | |
| SCHEMBL1737380 | 0.89 | MAPT (0.41) | PIK3CBPIK3CDPIK3CAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1737248 | 0.88 | MAPT (0.40) | PIK3CBPIK3CDPIK3CAKDM4EALDH1A1 | |
| SCHEMBL1738725 | 0.88 | MAPT (0.38) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1736624 | 0.87 | MAPT (0.38) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1736282 | 0.86 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2PDE1APDE1B | |
| SCHEMBL1735946 | 0.85 | MAPT (0.36) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1735595 | 0.85 | MAPT (0.37) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1737192 | 0.85 | GRIN2D (0.43) | PIK3CDKDM4EALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL1735624 | 0.85 | LMNA (0.43) | ALDH1A1LMNASMN1; SMN2PDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |