Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1735624 | 0.99 | LMNA (0.43) | LMNAPOLBALDH1A1SMN1; SMN2PLA2G1B | |
| SCHEMBL1737529 | 0.92 | TP53 (0.38) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1739451 | 0.92 | L3MBTL1 (0.38) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1737447 | 0.92 | LMNA (0.47) | LMNAPOLBALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL1738183 | 0.92 | L3MBTL1 (0.38) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736923 | 0.92 | TP53 (0.37) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736967 | 0.91 | LMNA (0.47) | LMNAPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1739793 | 0.90 | LMNA (0.45) | LMNAALDH1A1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL1735922 | 0.89 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1735623 | 0.88 | FABP3 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |