Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738362 | 0.99 | SIGMAR1 (0.40) | SIGMAR1PRMT5WDR77ALDH1A1MAPT | |
| SCHEMBL1739789 | 0.91 | MCL1 (0.36) | PRMT5WDR77ALDH1A1MAPTMEN1 | |
| SCHEMBL1737872 | 0.91 | FABP4 (0.39) | SIGMAR1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1738675 | 0.90 | SIGMAR1 (0.39) | SIGMAR1PRMT5WDR77ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1736972 | 0.90 | MCL1 (0.35) | SIGMAR1PRMT5WDR77ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1737082 | 0.90 | FABP4 (0.38) | SIGMAR1KDM4EMEN1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL1737200 | 0.90 | SIGMAR1 (0.40) | SIGMAR1PRMT5WDR77ALDH1A1MAPT | |
| SCHEMBL1738008 | 0.89 | MEN1 (0.37) | KDM4EMEN1RAB9AKMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL1737626 | 0.89 | MEN1 (0.36) | KDM4EMEN1RAB9AKMT2AALOX15 | |
| SCHEMBL1739794 | 0.88 | SIGMAR1 (0.41) | SIGMAR1PRMT5WDR77ALDH1A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |