Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736557 | 0.99 | KMT2A (0.35) | TSHRRAB9AKMT2ANPC1TP53 | |
| SCHEMBL1736127 | 0.89 | DYRK1A (0.40) | RAB9AKMT2ANPC1TP53KDM4E | |
| Hydrochloric Acid SCHEMBL1736588 | 0.88 | DYRK1A (0.39) | RAB9AKMT2ANPC1TP53KDM4E | |
| SCHEMBL1737474 | 0.87 | DYRK1A (0.38) | RAB9AKMT2ANPC1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1737703 | 0.86 | DYRK1A (0.37) | RAB9AKMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL1737062 | 0.85 | RAB9A (0.49) | TSHRRAB9AKMT2ANPC1TP53 | |
| Hydrochloric Acid SCHEMBL1736429 | 0.84 | RAB9A (0.48) | TSHRRAB9AKMT2ANPC1TP53 | |
| SCHEMBL1739067 | 0.84 | RAB9A (0.41) | TSHRRAB9AKMT2ANPC1TP53 | |
| SCHEMBL1737540 | 0.84 | PTGDR2 (0.38) | RAB9AKMT2ANPC1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1736057 | 0.84 | RAB9A (0.40) | TSHRRAB9AKMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |