SCHEMBL989802

SCHEMBL989802

CNC(=O)C(N)Cc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.63
ALPI P09923 1/20 0.63
PKM P14618 1/20 0.63
PTGS1 P23219 1/20 0.63
XIAP P98170 1/20 0.63
SLC15A1 P46059 1/20 0.59
CTSC P53634 2/20 0.58
LTA4H P09960 1/20 0.56
ANPEP P15144 1/20 0.51
RNPEP Q9H4A4 1/20 0.51
DNPEP Q9ULA0 1/20 0.51
BACE1 P56817 2/20 0.50
CTRB1 P17538 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648961 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL583592 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL1262434 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6164795 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6164804 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL7268667 0.92 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL6967778 0.92 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3704073 0.90 CTSC (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3704071 0.90 CTSC (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL20669159 0.87 MMP1 (0.61) CTSCMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010049405-A1 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2010-05-06 WO claimed
US-6486193-B2 ANTIARTHRITIC AGENTS; ANTIINFLAMMATORY AGENTS AVENTIS PHARMACEUTICALS INC. 2002-11-26 US claimed
US-20020037859-A1 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases AVENTISUB INC. 2002-03-28 US claimed
US-5290794-A Storage stable compositions WARNER LAMBERT CO. (US) 1994-03-01 US claimed
CN-120004785-A Compounds and compositions for the treatment of diseases associated with STING activity 诺华制药股份有限公司 2025-05-16 CN disclosed
CN-112823036-B Compounds and compositions for the treatment of diseases associated with STING activity 艾福姆德尤股份有限公司 2024-11-08 CN disclosed
US-20240083895-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2024-03-14 US disclosed
CN-117561058-A CDK2 inhibitors and methods of use thereof 塞迪拉治疗股份有限公司 2024-02-13 CN disclosed
US-11618749-B2 Compounds and compositions for treating conditions associated with STING activity IFM DUE, INC. (US) 2023-04-04 US disclosed
EP-3707140-B1 PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS COUNCIL SCIENT IND RES (IN) 2021-10-13 EP disclosed
CN-112823036-A Compounds and compositions for treating diseases associated with STING activity 艾福姆德尤股份有限公司 2021-05-18 CN disclosed
EP-3817820-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM Due, Inc. (US) 2021-05-12 EP disclosed
WO-1992013831-A1 HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-08-20 WO disclosed
EP-0495013-A1 HEXAPEPTIDES WITH SULPHATE ESTER GROUPS. FISONS CORP (US) 1992-07-22 EP disclosed
EP-0446267-A1 HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS. BRITISH BIO TECHNOLOGY (GB) 1991-09-18 EP disclosed
WO-1991008225-A1 HEXAPEPTIDES WITH SULPHATE ESTER GROUPS FISONS CORPORATION (US) 1991-06-13 WO disclosed
EP-0376012-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP disclosed
EP-0376040-A2 N-phosphinyl di-and tripeptides as renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP disclosed
WO-1990005719-A1 HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1990-05-31 WO disclosed
EP-0224151-A2 2-Substituted-[2-substituted-amino]-N-aralkyl-3-[indol-3-yl]propanamides WARNER-LAMBERT COMPANY (US) 1987-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11618749-B2 Compounds and compositions for treating conditions associated with STING activity STING1, IRF3, CGAS SLC7A5 3240/4885ALPI 1701/4885PKM 3471/4885
US-20240083895-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 SLC7A5 3202/4885ALPI 2124/4885PKM 3505/4885
US-20020037859-A1 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases MMP3, MMP1, MMP9 SLC7A5 2741/4885ALPI 289/4885PKM 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.