Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16012027 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL16012277 | 0.93 | ATM (0.35) | HDAC8REN | |
| SCHEMBL16012278 | 0.93 | ATM (0.35) | HDAC8REN | |
| SCHEMBL17268784 | 0.88 | HDAC8 (0.36) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL16012130 | 0.88 | PEPD (0.36) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL17364144 | 0.88 | PEPD (0.36) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL15672745 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL19457997 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL17138057 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MMP2ANPEPHDAC8PEPD | |
| SCHEMBL4430070 | 0.84 | HDAC1 (0.41) | ALDH1A1MMP2ANPEPHDAC8PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580463-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2964664-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-01-11 | — | — | EP | disclosed |
| US-20150376233-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376233-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, HCCS, GOT1 | ALDH1A1 421/4885MMP2 875/4885ANPEP 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.