Tiformin

Tiformin

SCHEMBL1736430

NC(=O)CCCN=C(N)N

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
NFKB1 P19838 2/20 0.52
ALOX15 P16050 1/20 0.52
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
GLA P06280 1/20 0.50
TSHR P16473 1/20 0.50
APEX1 P27695 1/20 0.50
CYP2C19 P33261 1/20 0.50
NOS2 P35228 1/20 0.50
DHPS P49366 1/20 0.50
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM1 P11229 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31147718 0.92 CHRM2 (0.57) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL1743686 0.84 CYP1A2 (0.52) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL1735347 0.80 CYP1A2 (0.48) CYP1A2NFKB1ALOX15MAOAMAOB
Arcaine SCHEMBL1737639 0.78 CYP1A2 (0.77) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL1736351 0.78 CYP1A2 (0.67) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL4670166 0.77 CHRM2 (0.53) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL1736310 0.76 DHPS (0.78) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL5541512 0.75 CHRM2 (0.56) CYP1A2NFKB1ALOX15MAOAMAOB
SCHEMBL138507 0.74
Hydrochloric Acid SCHEMBL21715459 0.73 DHPS (0.74) CYP1A2NFKB1ALOX15MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812738-B2 Polynucleotide molecules for gene regulation in plants MONSANTO TECHNOLOGY LLC (US) 2023-11-14 US disclosed
EP-3042718-A1 DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2016-07-13 EP disclosed
US-20160122686-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-05-05 US disclosed
CN-103038195-B Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by micro-or nanoemulsification ULRICH DIETZ (DE) 2016-04-13 CN disclosed
EP-2585420-B1 METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-04-06 EP disclosed
US-9127233-B2 Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification Dietz, Ulrich (DE) 2015-09-08 US disclosed
EP-2585420-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2013-05-01 EP disclosed
US-20130090488-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2013-04-11 US disclosed
CN-103038195-A Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by micro-or nanoemulsification DIETZ ULRICH 2013-04-10 CN disclosed
WO-2011160857-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2011-12-29 WO disclosed
EP-2399885-A1 Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification Dietz, Ulrich (DE) 2011-12-28 EP disclosed