Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426822 | 0.91 | MAOA (0.60) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL22181586 | 0.91 | MAOA (0.60) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL30461144 | 0.89 | NPC1 (0.55) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL5255935 | 0.89 | NPC1 (0.55) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL4748638 | 0.89 | NPC1 (0.55) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL30622749 | 0.89 | NPC1 (0.55) | NPC1RAB9ATDP1TSHRALDH1A1 | |
| SCHEMBL5543437 | 0.85 | MAOA (0.66) | NPC1RAB9ATDP1ALDH1A1POLB | |
| SCHEMBL21657641 | 0.84 | MAOA (0.54) | NPC1RAB9ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29928402 | 0.84 | MAOA (0.54) | NPC1RAB9ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30855377 | 0.84 | NPC1 (0.59) | NPC1RAB9ATDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221949-B2 | Resin, optical material, and optical device | MITSUI CHEMICALS, INC. (JP) | 2015-12-29 | — | — | US | disclosed |