SCHEMBL1736537

SCHEMBL1736537

NC(N)=Nc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS3 P29474 4/20 0.68
▸ NOS1 P29475 4/20 0.68
▸ NOS2 P35228 4/20 0.68
▸ TPH1 P17752 1/20 0.64
▸ SLC7A5 Q01650 3/20 0.61
▸ PTGS1 P23219 3/20 0.59
▸ ALPI P09923 1/20 0.59
▸ PKM P14618 1/20 0.59
▸ XIAP P98170 1/20 0.59
▸ ITGB3 P05106 1/20 0.59
▸ ITGAV P06756 1/20 0.59
▸ ITGA2B P08514 1/20 0.59
▸ ADRA2A P08913 2/20 0.53
▸ ADRA2B P18089 1/20 0.53
▸ ADRA2C P18825 1/20 0.53
▸ PLAU P00749 2/20 0.52
▸ ALOX15 P16050 3/20 0.51
▸ HIF1A Q16665 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ TDP1 Q9NUW8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22344276 1.00 NOS3 (0.68) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL2310526 0.83 SLC7A5 (0.83) TPH1SLC7A5PTGS1ALPIPKM
SCHEMBL11981895 0.82 SLC7A5 (0.65) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL22904679 0.82 SLC7A5 (0.65) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL3670851 0.80 SLC7A5 (0.71) TPH1SLC7A5PTGS1ALPIPKM
SCHEMBL1736460 0.79 TPH1 (0.64) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL19368127 0.79 SLC7A5 (0.70) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL5286259 0.79 SLC7A5 (0.70) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL12272708 0.79 SLC7A5 (0.70) NOS3NOS1NOS2TPH1SLC7A5
SCHEMBL1712908 0.79 SLC7A5 (0.70) NOS3NOS1NOS2TPH1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF WNTRX PHARMACEUTICALS INC. 2024-09-26 — — US disclosed
US-11591365-B2 BCL9 peptides and variants thereof WNTRX PHARMACEUTICALS INC. (US) 2023-02-28 — — US disclosed
US-11591365-B2 BCL9 peptides and variants thereof WNTRX PHARMACEUTICALS INC. (US) 2023-02-28 — — US disclosed
CN-111836632-A BCL9 peptides and variants thereof 温特瑞克斯制药有限公司 2020-10-27 — — CN disclosed
US-20200262867-A1 BCL9 PEPTIDES AND VARIANTS THEREOF WNTRX PHARMACEUTICALS INC. 2020-08-20 — — US disclosed
US-20200262867-A1 BCL9 PEPTIDES AND VARIANTS THEREOF WNTRX PHARMACEUTICALS INC. 2020-08-20 — — US disclosed
EP-3042718-A1 DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2016-07-13 — — EP disclosed
US-20160122686-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-05-05 — — US disclosed
CN-103038195-B Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by micro-or nanoemulsification ULRICH DIETZ (DE) 2016-04-13 — — CN disclosed
EP-2585420-B1 METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-04-06 — — EP disclosed
US-9127233-B2 Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification Dietz, Ulrich (DE) 2015-09-08 — — US disclosed
EP-2585420-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2013-05-01 — — EP disclosed
US-20130090488-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2013-04-11 — — US disclosed
WO-2011160857-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2011-12-29 — — WO disclosed
EP-2399885-A1 Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification Dietz, Ulrich (DE) 2011-12-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF BCL9, BCL9L, BCL3 NOS3 3893/4885NOS1 4459/4885NOS2 3517/4885
US-11591365-B2 BCL9 peptides and variants thereof BCL9, BCL9L, BCL3 NOS3 3893/4885NOS1 4459/4885NOS2 3517/4885
US-20200262867-A1 BCL9 PEPTIDES AND VARIANTS THEREOF BCL9, BCL9L, BCL3 NOS3 3893/4885NOS1 4459/4885NOS2 3517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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