Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30121977 | 0.90 | MDM2 (0.64) | MDM2MEN1KMT2AKDM4ETP53 | |
| SCHEMBL17366174 | 0.86 | MDM2 (0.58) | MDM2MEN1KMT2AKDM4ETP53 | |
| SCHEMBL17366169 | 0.84 | MDM2 (0.58) | MDM2TP53CASP3MAPTALDH1A1 | |
| SCHEMBL17366151 | 0.84 | MDM2 (0.58) | MDM2MEN1KMT2AKDM4ETP53 | |
| SCHEMBL17366156 | 0.82 | MDM2 (0.60) | MDM2MEN1KMT2AKDM4ETP53 | |
| SCHEMBL17366170 | 0.81 | MDM2 (0.64) | MDM2MEN1KMT2ATP53MAPT | |
| SCHEMBL17366150 | 0.81 | MDM2 (0.55) | MDM2TP53ALDH1A1 | |
| SCHEMBL30296389 | 0.80 | KDM4E (0.66) | MEN1KMT2AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL2644150 | 0.80 | KDM4E (0.66) | MEN1KMT2AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL31370999 | 0.80 | KDM4E (0.53) | MEN1KMT2AKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | disclosed |
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |