SCHEMBL17366190

SCHEMBL17366190

CC1CC1(C)OOC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
F2 P00734 1/20 0.52
GAA P10253 1/20 0.49
TSHR P16473 4/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 4/20 0.43
CHRNA7 P36544 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
MEN1 O00255 2/20 0.40
MAPK1 P28482 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
MAPT P10636 1/20 0.39
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615171 0.77 LMNA (0.57) LMNAF2GAATSHRALDH1A1
SCHEMBL10342886 0.76 LMNA (0.43) LMNAF2GAATSHRALDH1A1
SCHEMBL1426503 0.74 GAA (0.49) LMNAF2GAATSHRALDH1A1
Benzoyl Peroxide SCHEMBL27699306 0.71 LMNA (0.90) LMNAF2TSHRALDH1A1HSD17B10
SCHEMBL28929252 0.71 GAA (0.46) LMNAF2GAATSHRALDH1A1
Benzoyl Peroxide SCHEMBL63 0.71 LMNA (1.00) LMNAF2TSHRALDH1A1HSD17B10
Benzoyl Peroxide SCHEMBL2929886 0.71 LMNA (1.00) LMNAF2TSHRALDH1A1HSD17B10
Benzoyl Peroxide SCHEMBL5312311 0.71 LMNA (1.00) LMNAF2TSHRALDH1A1HSD17B10
Benzoyl Peroxide SCHEMBL9407293 0.71 LMNA (1.00) LMNAF2TSHRALDH1A1HSD17B10
Benzoyl Peroxide SCHEMBL3467853 0.71 LMNA (1.00) LMNAF2TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2032669-B1 FUNCTIONALIZED OLEFIN INTERPOLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-30 EP disclosed