SCHEMBL1426503

SCHEMBL1426503

CC1CC1(OC(=O)c1ccccc1)C1(OC(=O)c2ccccc2)CC1C

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
TSHR P16473 6/20 0.48
LMNA P02545 2/20 0.47
F2 P00734 1/20 0.47
KMT2A Q03164 3/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
CHRNA7 P36544 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28929252 0.82 GAA (0.46) GAATSHRLMNAF2KMT2A
SCHEMBL29867855 0.81 GAA (0.43) GAATSHRLMNAF2KMT2A
SCHEMBL30526381 0.76 F2 (0.48) GAATSHRLMNAF2KMT2A
SCHEMBL29893765 0.74 GAA (0.49) GAATSHRLMNAF2KMT2A
SCHEMBL17366190 0.74 LMNA (0.52) GAATSHRLMNAF2KMT2A
SCHEMBL16861396 0.73 TSHR (0.52) GAATSHRLMNAF2KMT2A
SCHEMBL38660477 0.73 TSHR (0.47) GAATSHRLMNAF2KMT2A
SCHEMBL11575818 0.73 FAAH (0.51) GAATSHRLMNAF2ALDH1A1
SCHEMBL12151609 0.73 GAA (0.44) GAATSHRLMNAF2KMT2A
SCHEMBL1784677 0.71 TSHR (0.54) GAATSHRLMNAF2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2300532-B1 PVC-BASED FLAME-RETARDANT COMPOSITION PORCHER IND (FR) 2022-11-09 EP claimed
EP-3348529-A1 SEALER COMPOSITION FOR EDGE SEALING OF INSULATION GLASS Dana Lim A/S (DK) 2018-07-18 EP claimed
EP-2300532-B1 PVC-BASED FLAME-RETARDANT COMPOSITION PORCHER IND (FR) 2022-11-09 EP disclosed
EP-3475084-A1 MULTILAYER ARTICLES WITH A BARRIER FILM INCLUDING A THERMOPLASTIC ALIPHATIC POLYESTER, A POLYVINYL ALKANOATE POLYMER, AND A PLASTICIZER 3M Innovative Properties Company (US) 2019-05-01 EP disclosed
US-20190099991-A1 MULTILAYER ARTICLES WITH A BARRIER FILM INCLUDING A THERMOPLASTIC ALIPHATIC POLYESTER, A POLYVINYL ALKANOATE POLYMER, AND A PLASTICIZER 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-04-04 US disclosed
US-10138576-B2 Biocompatible hydrophilic compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-27 US disclosed
EP-3348529-A1 SEALER COMPOSITION FOR EDGE SEALING OF INSULATION GLASS Dana Lim A/S (DK) 2018-07-18 EP disclosed
WO-2017222863-A1 MULTILAYER ARTICLES WITH A BARRIER FILM INCLUDING A THERMOPLASTIC ALIPHATIC POLYESTER, A POLYVINYL ALKANOATE POLYMER, AND A PLASTICIZER 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-12-28 WO disclosed
US-9611572-B2 Dimensionally stable nonwoven fibrous webs, and methods of making and using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-04-04 US disclosed
US-9416485-B2 Process of making dimensionally stable nonwoven fibrous webs 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-08-16 US disclosed
EP-2539496-B1 DIMENSIONALLY STABLE NONWOVEN FIBROUS WEBS AND METHODS OF MAKING AND USING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2016-02-10 EP disclosed
EP-1747029-A1 AN IODINE-CONTAINING HOT MELT PRESSURE SENSITIVE ADHESIVE CAPABLE OF BEING MELTED AND COATED AT A TEMPERATURE NOT HIGHER THAN 100° C, AND A MEDICAL ADHESIVE SHEET PRODUCT WITH SUCH A PRESSURE SENSITIVE ADHESIVE 3M Innovative Properties Company (US) 2007-01-31 EP disclosed
EP-1497389-B1 Methods of making an iodine/iodide-complex containing, hot melt coatable adhesive 3M INNOVATIVE PROPERTIES CO (US) 2007-01-24 EP disclosed
WO-2005113029-A1 AN IODINE-CONTAINING HOT MELT PRESSURE SENSITIVE ADHESIVE CAPABLE OF BEING MELTED AND COATED AT A TEMPERATURE NOT HIGHER THAN 100° C, AND A MEDICAL ADHESIVE SHEET PRODUCT WITH SUCH A PRESSURE SENSITIVE ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-01 WO disclosed
US-20050202070-A1 Iodine/iodide-containing hot melt coatable adhesive, methods and uses therefor 3M INNOVATIVE PROPERTIES COMPANY 2005-09-15 US disclosed
US-6939936-B2 Iodine/iodide-containing hot melt coatable adhesive, methods and uses therefor 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-09-06 US disclosed
EP-1497389-A1 IODINE/IODIDE-CONTAINING HOT MELT COATABLE ADHESIVE, METHODS AND USES THEREFOR 3M Innovative Properties Company (US) 2005-01-19 EP disclosed
US-20030212176-A1 Iodine/iodide-containing hot melt coatable adhesive, methods and uses therefor 3M INNOVATIVE PROPERTIES COMPANY 2003-11-13 US disclosed
WO-2003091354-A1 IODINE/IODIDE-CONTAINING HOT MELT COATABLE ADHESIVE, METHODS AND USES THEREFOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-11-06 WO disclosed
US-5338786-A Storage stability; containing a thiophene compounds and an arylsulphoryisocyanate compound CHEMICAL INVESTMENTS, LTD. (GB) 1994-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10138576-B2 Biocompatible hydrophilic compositions CD44, CD68, EPCAM GAA 2858/4885TSHR 3734/4885LMNA 738/4885
US-20050202070-A1 Iodine/iodide-containing hot melt coatable adhesive, methods and uses therefor ICAM1, MMP1, MACF1 GAA 4666/4885TSHR 2406/4885LMNA 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.