Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PTDSS1 | P48651 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366184 | 0.82 | MDM2 (0.46) | MDM2TP53 | |
| SCHEMBL17366169 | 0.69 | MDM2 (0.58) | MDM2TP53MAPTTRPM8 | |
| SCHEMBL30121977 | 0.68 | MDM2 (0.64) | MDM2TP53MAPT | |
| SCHEMBL17366161 | 0.66 | MDM2 (0.51) | MDM2TP53MAPT | |
| SCHEMBL29872333 | 0.65 | TP53 (0.38) | MDM2TP53MAPTPTDSS1 | |
| SCHEMBL17366153 | 0.65 | MDM2 (0.52) | MDM2TP53 | |
| SCHEMBL17366182 | 0.65 | MDM2 (0.56) | MDM2TP53MAPT | |
| SCHEMBL31520186 | 0.65 | MDM2 (0.45) | MDM2TP53MAPTRXFP1PTDSS1 | |
| SCHEMBL30122194 | 0.64 | MDM2 (0.41) | MDM2TP53 | |
| SCHEMBL17366151 | 0.64 | MDM2 (0.58) | MDM2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | disclosed |
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |