Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 14/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366150 | 0.85 | MDM2 (0.55) | MDM2TP53ALDH1A1HTTNPSR1 | |
| SCHEMBL17366167 | 0.85 | MDM2 (0.48) | MDM2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL17366181 | 0.83 | MDM2 (0.51) | MDM2TP53CA12CA2CA9 | |
| SCHEMBL17366153 | 0.81 | MDM2 (0.52) | MDM2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL30121977 | 0.73 | MDM2 (0.64) | MDM2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL31520186 | 0.71 | MDM2 (0.45) | MDM2TP53MEN1KMT2AMAPT | |
| SCHEMBL17366169 | 0.69 | MDM2 (0.58) | MDM2TP53ALDH1A1HTTNPSR1 | |
| SCHEMBL17366174 | 0.69 | MDM2 (0.58) | MDM2TP53KDM4EALDH1A1HTT | |
| SCHEMBL17366151 | 0.69 | MDM2 (0.58) | MDM2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL17366177 | 0.68 | MEN1 (0.48) | MDM2TP53KDM4ENPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | disclosed |
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |