Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366257 | 0.86 | MCHR1 (0.48) | MCHR1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL11230411 | 0.86 | ALDH1A1 (0.42) | MCHR1ALDH1A1GAASLC2A1MAPT | |
| SCHEMBL10188117 | 0.81 | SMN1; SMN2 (0.41) | MCHR1SLC2A1KDM4EMEN1KMT2A | |
| SCHEMBL3704321 | 0.81 | ALDH1A1 (0.48) | MCHR1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL18727243 | 0.81 | KDM4E (0.57) | MCHR1ALDH1A1GAASLC2A1MAPT | |
| SCHEMBL12817393 | 0.79 | TSHR (0.57) | ALDH1A1GAASLC2A1MAPTKDM4E | |
| SCHEMBL17366270 | 0.79 | MCHR1 (0.39) | MCHR1ALDH1A1SLC2A1SMN1; SMN2TSHR | |
| SCHEMBL9856093 | 0.79 | S1PR1 (0.45) | MCHR1SLC2A1TSHRHTR2AHTR2C | |
| SCHEMBL13925425 | 0.79 | HTT (0.43) | MCHR1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL28299808 | 0.77 | ALDH1A1 (0.58) | MCHR1ALDH1A1GAASLC2A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |