Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584342 | 0.84 | MCHR1 (0.38) | MCHR1 | |
| SCHEMBL10188117 | 0.81 | SMN1; SMN2 (0.41) | MCHR1SLC2A1P2RX3SMN1; SMN2 | |
| SCHEMBL6112972 | 0.81 | TSHR (0.39) | MCHR1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL17366256 | 0.79 | MCHR1 (0.45) | MCHR1SLC2A1TSHRHTR2AHTR2C | |
| SCHEMBL12817393 | 0.79 | TSHR (0.57) | SLC2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9856093 | 0.79 | S1PR1 (0.45) | MCHR1SLC2A1TSHRHTR2AHTR2C | |
| SCHEMBL13925425 | 0.79 | HTT (0.43) | MCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2794945 | 0.76 | ALDH1A1 (0.38) | TSHRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL29957805 | 0.75 | PPARA (0.36) | MCHR1SLC2A1TSHRHTR2AHTR2C | |
| SCHEMBL24592701 | 0.73 | RORC (0.41) | MCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |