Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490284 | 0.85 | MCHR1 (0.51) | ALDH1A1MCHR1LMNAMAPT | |
| SCHEMBL17366254 | 0.85 | MCHR1 (0.48) | ALDH1A1GAAL3MBTL1MCHR1LMNA | |
| SCHEMBL20269984 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAAL3MBTL1MCHR1LMNA | |
| SCHEMBL8596342 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GAAL3MBTL1LMNAPPARG | |
| SCHEMBL9060740 | 0.80 | L3MBTL1 (0.44) | ALDH1A1GAAL3MBTL1MCHR1LMNA | |
| SCHEMBL9060171 | 0.80 | L3MBTL1 (0.44) | ALDH1A1GAAL3MBTL1MCHR1LMNA | |
| SCHEMBL104729 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GAAL3MBTL1LMNAPPARG | |
| SCHEMBL17070600 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GAAL3MBTL1LMNAPPARG | |
| SCHEMBL27290749 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAL3MBTL1LMNAPPARG | |
| SCHEMBL28470780 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAL3MBTL1LMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |