Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 14/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366255 | 0.85 | DRD4 (0.46) | DRD4ADRA2CRAB9A | |
| SCHEMBL12180342 | 0.77 | PDE10A (0.51) | DRD4NPC1CASP3RAB9ASENP7 | |
| SCHEMBL15651365 | 0.76 | DRD4 (0.51) | DRD4ADRA2CNPC1CASP3RAB9A | |
| SCHEMBL14320514 | 0.76 | DRD4 (0.51) | DRD4ADRA2CNPC1CASP3RAB9A | |
| SCHEMBL15651821 | 0.76 | DRD4 (0.51) | DRD4ADRA2CNPC1CASP3RAB9A | |
| SCHEMBL20820540 | 0.75 | MAPT (0.50) | DRD4NPC1CASP3RAB9ASENP7 | |
| SCHEMBL3182576 | 0.75 | DRD4 (0.50) | DRD4ADRA2CNPC1CASP3RAB9A | |
| SCHEMBL17811807 | 0.74 | NPC1 (0.44) | DRD4ADRA2CNPC1CASP3RAB9A | |
| SCHEMBL11490890 | 0.73 | ADRA2C (0.63) | DRD4ADRA2C | |
| SCHEMBL11439070 | 0.72 | KDM4E (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |