Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366268 | 0.85 | DRD4 (0.61) | DRD4RAB9AADRA2C | |
| SCHEMBL10188107 | 0.84 | RAB9A (0.52) | ALDH1A1GLAMAPTRAB9ATSHR | |
| SCHEMBL17366258 | 0.82 | SSTR4 (0.43) | ALDH1A1GLASSTR4HTR2AHTR2B | |
| SCHEMBL12180345 | 0.77 | RAB9A (0.62) | ALDH1A1GLAMAPTRAB9ATSHR | |
| SCHEMBL3052373 | 0.74 | RAB9A (0.44) | DRD4ALDH1A1GLAMAPTRAB9A | |
| SCHEMBL1020226 | 0.72 | ESR1 (0.46) | DRD4ALDH1A1SSTR4MAPTRAB9A | |
| SCHEMBL15337638 | 0.72 | RAB9A (0.42) | ALDH1A1GLAMAPTRAB9ATSHR | |
| SCHEMBL17908114 | 0.71 | PTGER1 (0.56) | ALDH1A1MAPTRAB9ATSHRSMN1; SMN2 | |
| SCHEMBL28724733 | 0.71 | RAB9A (0.41) | ALDH1A1GLAMAPTRAB9ATSHR | |
| SCHEMBL28724732 | 0.71 | RAB9A (0.41) | ALDH1A1GLAMAPTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |