Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838849 | 0.86 | MCHR1 (0.54) | MCHR1ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL11915275 | 0.85 | MCHR1 (0.45) | MCHR1ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL10408218 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL11708358 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL10866638 | 0.80 | ADRA2A (0.44) | ALDH1A1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL3162558 | 0.79 | ADRA2A (0.43) | ALDH1A1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL10408220 | 0.79 | KMT2A (0.45) | ALDH1A1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL10869047 | 0.78 | MCHR1 (0.48) | MCHR1ALDH1A1HPGDMAPTTAS1R3 | |
| SCHEMBL22513126 | 0.78 | MCHR1 (0.48) | MCHR1ADRA2AADRA2BADRA2CHPGD | |
| SCHEMBL17366254 | 0.78 | MCHR1 (0.48) | MCHR1ALDH1A1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |