Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.45 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Batilol SCHEMBL8734525 | 0.98 | USP2 (0.83) | USP2LPAR5HTTLPAR3LPAR1 | |
| Batilol SCHEMBL27670623 | 0.98 | USP2 (0.83) | USP2LPAR5HTTLPAR3LPAR1 | |
| Phosphoric Acid SCHEMBL28262922 | 0.98 | USP2 (0.83) | USP2LPAR5HTTLPAR3LPAR1 | |
| Phosphoric Acid SCHEMBL9346185 | 0.98 | USP2 (0.83) | USP2LPAR5HTTLPAR3LPAR1 | |
| Phosphoric Acid SCHEMBL7810837 | 0.98 | USP2 (0.83) | USP2LPAR5HTTLPAR3LPAR1 | |
| SCHEMBL11294392 | 0.91 | USP2 (0.96) | USP2LPAR5HTTLPAR3LPAR1 | |
| SCHEMBL5527804 | 0.91 | USP2 (0.96) | USP2LPAR5HTTLPAR3LPAR1 | |
| SCHEMBL11158 | 0.91 | USP2 (0.96) | USP2LPAR5HTTLPAR3LPAR1 | |
| Pyrophosphoric Acid SCHEMBL9446702 | 0.90 | USP2 (0.75) | USP2LPAR5HTTLPAR3LPAR1 | |
| Phosphoric Acid SCHEMBL4016770 | 0.89 | USP2 (0.69) | USP2LPAR5HTTLPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024079137-A1 | INCREASING LEAF BIOMASS AND NITROGEN USE EFFICIENCY BY REGULATING NTP2 | PHILIP MORRIS PRODUCTS S.A. (CH) | 2024-04-18 | — | — | WO | disclosed |
| EP-3169149-B1 | TOBACCO PROTEASE GENES | PHILIP MORRIS PRODUCTS SA (CH) | 2024-01-17 | — | — | EP | disclosed |
| WO-2023117661-A1 | INCREASING ANATABINE IN TOBACCO LEAF BY REGULATING METHYL PUTRESCINE OXIDASE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023117701-A1 | MODULATION OF NICOTINE PRODUCTION BY ALTERATION OF NICOTINAMIDASE EXPRESSION OR FUNCTION IN PLANTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-06-29 | — | — | WO | disclosed |
| US-20230200344-A1 | MODULATING SUGAR AND AMINO ACID CONTENT IN A PLANT (SULTR3) | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-06-29 | — | — | US | disclosed |
| US-11685929-B2 | Plants with shortened time to flowering | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-06-27 | — | — | US | disclosed |
| US-11591609-B2 | Modulating reducing sugar content in a plant | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-02-28 | — | — | US | disclosed |
| EP-4041753-A1 | MODULATING SUGAR AND AMINO ACID CONTENT IN A PLANT (SULTR3) | Philip Morris Products S.A. (CH) | 2022-08-17 | — | — | EP | disclosed |
| US-11213004-B2 | Reducing cadmium accumulation in field grown tobacco plants | PHILIP MORRIS PRODUCTS S.A. (CH) | 2022-01-04 | — | — | US | disclosed |
| US-20210115461-A1 | MODULATING AMINO ACID CONTENT IN A PLANT | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-04-22 | — | — | US | disclosed |
| US-20030069179-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-04-10 | — | — | US | disclosed |
| US-20030064925-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-04-03 | — | — | US | disclosed |
| US-20030065142-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-04-03 | — | — | US | disclosed |
| US-20030064062-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-04-03 | — | — | US | disclosed |
| US-20030054406-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-03-20 | — | — | US | disclosed |
| US-20030044841-A1 | Secreted and transmembrane polypeptides and nucleic acids encoding the same | GENENTECH, INC. | 2003-03-06 | — | — | US | disclosed |
| EP-1144629-A3 | FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF | Genentech, Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-1144629-A2 | FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF | Genentech, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000078961-A1 | SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME | GENENTECH, INC. (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000012708-A2 | FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF | GENENTECH, INC. (US) | 2000-03-09 | — | — | WO | disclosed |