Phosphoric Acid

Phosphoric Acid

SCHEMBL4016770

CCCCCCCC/C=C\CCCCCCCCOCC(O)CO.O=P(O)(O)O

nearest known ligand 0.76

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.69
P2RY10 O00398 2/20 0.60
LPAR5 Q9H1C0 1/20 0.58
DGKA P23743 1/20 0.57
LPAR1 Q92633 6/20 0.54
LPAR3 Q9UBY5 4/20 0.54
LPAR2 Q9HBW0 1/20 0.51
FAAH O00519 2/20 0.51
HTT P42858 1/20 0.50
SELP P16109 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4016778 1.00 USP2 (0.69) USP2P2RY10LPAR5DGKALPAR1
SCHEMBL2231761 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL8577431 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL7065281 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL7064549 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL2232602 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL1962549 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL81179 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL81180 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3
SCHEMBL15418245 0.93 USP2 (0.80) USP2P2RY10DGKALPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100595892-C Polishing composition SHOWA DENKO KK 2010-03-24 CN disclosed
US-20090289217-A1 POLISHING COMPOSITION SHOWA DENKO K.K. (JP) 2009-11-26 US disclosed
US-20090194504-A1 METHOD FOR PRODUCING ABRASIVE COMPOSITION SHOWA DENKO K.K. (JP) 2009-08-06 US disclosed
EP-2075824-A1 POLISHING COMPOSITION SHOWA DENKO KABUSHIKI KAISHA (JP) 2009-07-01 EP disclosed
EP-2019419-A1 METHOD FOR PRODUCING POLISHING COMPOSITION Showa Denko K.K. (JP) 2009-01-28 EP disclosed
CN-101160644-A Polishing composition SHOWA DENKO KK (JP) 2008-04-09 CN disclosed
US-20070128872-A1 Polishing composition and polishing method SHOWA DENKO K.K. (JP) 2007-06-07 US disclosed
EP-1687387-A1 POLISHING COMPOSITION COMPRISING PHOSPHATE ESTERS AND POLISHING METHOD Showa Denko K.K. (JP) 2006-08-09 EP disclosed
WO-2005047409-A1 POLISHING COMPOSITION AND POLISHING METHOD SHOWA DENKO K.K. (JP) 2005-05-26 WO disclosed