SCHEMBL17366451

SCHEMBL17366451

CNCN(C)CN(C)CO

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT1 Q99873 1/20 0.32
PRMT8 Q9NR22 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14578314 0.86 PRMT3 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12901248 0.83 PRMT3 (0.38) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13528590 0.80
SCHEMBL18649777 0.78
SCHEMBL18594754 0.78
SCHEMBL20362727 0.77
SCHEMBL21141421 0.77
SCHEMBL25923890 0.76 PRMT3 (0.33) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12901252 0.76 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14578306 0.74 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777116-B2 Porous/nanoporous PHT INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-10-03 US disclosed
US-9758620-B2 Tailorable viscoelastic properties of PEG-hemiaminal organogel networks INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-09-12 US disclosed
US-9676891-B2 Synthesis of dynamic covalent 3D constructs INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-06-13 US disclosed
US-20170145143-A1 SYNTHESIS OF DYNAMIC COVALENT 3D CONSTRUCTS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-05-25 US disclosed
US-20170114186-A1 POROUS/NANOPOROUS PHT INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-27 US disclosed
US-9598608-B2 Soluble, processable polyhemiaminals and polyhexahydrotriazines INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-03-21 US disclosed
US-20170066878-A1 TAILORABLE VISCOELASTIC PROPERTIES OF PEG-HEMIAMINAL ORGANOGEL NETWORKS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-03-09 US disclosed
US-20170066662-A1 METHODS AND APPARATUS FOR CONTROLLING METALS IN LIQUIDS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-03-09 US disclosed
US-9453108-B2 Flame retardant PHT compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-09-27 US disclosed
US-20160206744-A1 METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-07-21 US disclosed
US-20160108176-A1 POROUS/NANOPOROUS PHT INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-04-21 US disclosed
US-20150376442-A1 SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES INTERNATIONAL BUSINESS MACHINES CORPORATION 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160206744-A1 METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY PAICS, PHPT1, MAPT PRMT3 4389/4885CARM1 1792/4885PRMT6 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.