SCHEMBL12901252

SCHEMBL12901252

CNCN(C)CCN(C)CN(C)CNC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14578314 0.88 PRMT3 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12901248 0.85 PRMT3 (0.38) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL18467909 0.79 PIK3CD (0.43) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25923890 0.78 PRMT3 (0.33) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24764770 0.77
SCHEMBL15120327 0.76 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL17366451 0.76 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14578306 0.76 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13589014 0.75
SCHEMBL15919032 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110045027-A1 Adjuvant GLAXO GROUP LIMITED (GB) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110045027-A1 Adjuvant TLR3, TLR9, TLR7 PRMT3 2680/4885CARM1 3515/4885PRMT6 3689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.