SCHEMBL17366456

SCHEMBL17366456

CCN(CC)c1ccc(N2CN(c3ccc(N(CC)CC)cc3)CN(c3ccc(N4CN(c5ccc(N(C)C)cc5)CN(c5ccc(N6CN(c7ccc(C)cc7)CN(c7ccc(N)cc7)C6)cc5)C4)cc3)C2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.53
TDP1 Q9NUW8 6/20 0.53
MAPK1 P28482 3/20 0.53
TSHR P16473 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
GFER P55789 3/20 0.53
CYP3A4 P08684 2/20 0.53
PSMD14 O00487 1/20 0.53
RECQL P46063 1/20 0.53
ALOX15 P16050 2/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 8/20 0.43
LMNA P02545 3/20 0.43
HTT P42858 3/20 0.43
RAB9A P51151 2/20 0.43
POLB P06746 2/20 0.43
NPC1 O15118 1/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640899 0.82 ALDH1A1 (0.62) ALDH1A1TDP1MAPK1TSHRL3MBTL1
SCHEMBL8715756 0.80 ALDH1A1 (0.83) ALDH1A1TDP1MAPK1TSHRL3MBTL1
SCHEMBL7062536 0.74 ALDH1A1 (0.80) ALDH1A1TDP1MAPK1TSHRL3MBTL1
SCHEMBL16633168 0.74 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1TSHRL3MBTL1
SCHEMBL8467252 0.73 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1TSHRL3MBTL1
SCHEMBL33781 0.73 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1TSHRL3MBTL1
Diethylaniline SCHEMBL8678375 0.72 TSHR (0.58) ALDH1A1TDP1MAPK1TSHRL3MBTL1
Diethylaniline SCHEMBL27854140 0.72 TDP1 (0.67) ALDH1A1TDP1MAPK1TSHRL3MBTL1
Hydrochloric Acid SCHEMBL970321 0.71 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1TSHRL3MBTL1
Hydrochloric Acid SCHEMBL970320 0.71 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9598608-B2 Soluble, processable polyhemiaminals and polyhexahydrotriazines INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-03-21 US disclosed
US-9512332-B2 Soluble, processable polyhemiaminals and polyhexahydrotriazines INTERNATIONAL BUSUINESS MACHINES CORPORATION (US) 2016-12-06 US disclosed
US-20150376451-A1 SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES INTERNATIONAL BUSINESS MACHINES CORPORATION 2015-12-31 US disclosed
US-20150376442-A1 SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES INTERNATIONAL BUSINESS MACHINES CORPORATION 2015-12-31 US disclosed